参考文献

［1］吴雪琼，吴长有.结核病免疫学［M］.北京：人民卫生出版社，2016.

［2］唐神结，高文.临床结核病学［M］.北京：人民卫生出版社，2011.

［3］JAMES W D，BERGER T G，ELSTON D M.安得鲁斯临床皮肤病学［M］.徐世正，译.10版.北京：科学出版社，2008.

［4］白雪娟，吴雪琼.结核分枝杆菌潜伏感染相关抗原的研究进展［J］.中国防痨杂志，2014，36（33）:204-209.

［5］CAMBIER C J，FALKOW S，RAMAKRISHNAN L.Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis［J］.Cell，2014，159（7）:1497-509.

［6］EHRT S，SCHNAPPINGER D，RHEE K Y.Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis［J］.Nat Rev Microbiol，2018，16（8）:496-507.

［7］JASENOSKY L D，SCRIBA T J，HANEKOM W A，et al.T cells and adaptive immunity to Mycobacterium tuberculosis in humans［J］.Immunol Rev，2015，264（1）:74-87.

［8］HARTMAN M L，KORNFELD H.Interactions between naïve and infected macrophages reduce Mycobacterium tuberculosis viability［J］.PLoS One，2011，6（11）:e27972.

［9］CHOWDHURY R，VALLANIA F，YANG Q，et al.A multi-cohort study of the immune factors associated with M.tuberculosis infection outcomes［J］.Nature，2018，560（7720）:644-648.

［10］HUANG L，EVGENIYA V N，TAN S M，et al.Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny［J］.J Exp Med，2018，215（4）:1135-1152.

［11］MAHAMED D，BOULLE M，GANGA Y，et al.Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells［J］.Elife，2017（6）:e22028.

［12］MAERTZDORF J，TÖNNIES M，LOZZA L，et al.Mycobacterium tuberculosis Invasion of the Human Lung:First Contact［J］.Front Immunol，2018（9）:1346.

［13］CHANG K C，YEW W W.Management of difficult multidrug-resistant tuberculosis and extensively drugresistant tuberculosis:update 2012［J］.Respirololgy，2013，18（1）:8-21.

［14］SHU C C，WU V C，YANG F J，et al.Predictors and prevalenceof latent tuberculosis infection in patients receiving long-term he-modialysis and pentoneal dialysis［J］.PLoS One，2012，7（8）:e42592.

［15］FENG Y，DIAO N，SHAO L，et al.Interferon-gamma release performance in pulmonary and extrapulmonary tuberculosis［J］.PLoS One，2012，7（3）:e32652.

［16］CHEN J，ZHANG R，WANG J，et al.Interferon-gamma releaseassays for the diagnosis of active tuberculosis in HIV-infected patients:a systematic review and meta-analysis［J］.PLoS One，2011，6（11）:e26827.

［17］TANDON V，MAHAPATRA A K.Management of post-tubercular hydrocephalus［J］.Childs Nerv Syst，2011，27（10）:1699-1707.

［18］PASCO P M.Diagnostic features of tuberculous meningitis:across-sectional study［J］.BMC Res Notes，2012，5（1）:49.

［19］HMAMA Z，PENA-DIAZ S，JOSEPH S，et al.Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis［J］.Immunological reviews，2015（264）:220-232.

［20］LIU C H，LIU H，GE B.Innate immunity in tuberculosis:host defense vs pathogen evasion［J］.Cellular &molecular immunology，2017，14（12）:963-975.

［21］NETEA M G，WIJMENGA C，ONEILL L A.Genetic variation in Toll-like receptors and disease susceptibility［J］.Nat Immunol，2012，13（6）:535-542.

［22］SALIE M，DAYA M，LUCAS L A，et al.Association of toll-like receptors with susceptibility to tuberculosis suggests sex-specific effects of TLR8 polymorphisms［J］.Infect Genet Evol，2015（34）:221-229.

［23］SHIN J G，PARK B L，KIM L H，et al.Association study of polymorphisms in interferon-gamma receptor genes with the risk of pulmonary tuberculosis［J］.Mol Med Rep，2015，12（1）:1568-1578.

［24］ZHANG G，WEERD N A，STIFTER S A，et al.A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans［J］.Nat Commun，2018，9（1）:85.

［25］FACCHINI L，VENTURINI E，GALLI L，et al.Vitamin D and tuberculosis:a review on a hot topic［J］.J Chemother，2015，27（3）:128-138.

［26］LEE Y H，SONG G G.Vitamin D receptor gene FokI，TaqI，BsmI，and ApaI polymorphisms and susceptibility to pulmonary tuberculosis:a meta-analysis［J］.Genet Mol Res，2015，14（3）:9118-9129.

［27］YI YX，HAN J B，ZHAO L，et al.Tumor necrosis factor alpha gene polymorphism contributes to pulmonary tuberculosis susceptibility:evidence from a meta-analysis［J］.Int J Clin Exp Med，2015，8（11）:20690-20700.

［28］CURTIS J，LUO Y，ZENNER H L，et al.Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration［J］.Nat Genet，2015，47（5）:523-527.

［29］TOBIN D M，ROCA F J，OH S F，et al.Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections［J］.Cell，2012，148（3）:434-446. brDL2sQvjA2fR6HQYItC+IcbNUXwB0fuiUfNQlPr3+hqhq1Vw3tcpYFBQ2cLa3eF