参考文献

1.胡维新 .医学分子生物学 .2版 .北京 :科学出版社，2014

2.李艳，李金明 .个体化医疗中的临床分子诊断 .北京 :人民卫生出版社，2013

3.倪语星，尚红 .临床微生物学检验 .5版 .北京 :人民卫生出版社，2012

4.施红，蒋天安 .实用超声造影诊断学 .北京 :人民军医出版社，2013

5.王家，李绍白 .肝脏病学 .3版 .北京 :人民卫生出版社，2013

6.中华人民共和国国家卫生和计划生育委员会 .丙型病毒性肝炎筛查及管理 .传染病信息，2015（1）:1-2，22

7.陈新月，窦晓光，Hu D，等 .丙型肝炎病毒核心抗原实验室检测及其临床意义 .中国病毒病杂志，2013（01）:12-16

8.陈宇，姚新生，邱隆敏，等 .抗病毒治疗对CHB 患者外周血 TCRβ链CDR3谱系的影响.中国免疫学杂志，2014，30（1）:100-104

9.程力 .彩色多普勒超声在肝脏良恶性肿瘤中的应用 .中国现代普通外科进展，2013，16（10）:892-895

10.洪勇强.实时剪切波弹性成像在慢性乙型肝炎肝纤维化和炎症分级中的应用价值.中国慢性病预防与控制，2014，22（6）:737-739

11.李德忠，曾勇彬，苏明宽，等.监测HBsAg浓度对HBeAg阳性的慢性乙型肝炎患者恩替卡韦治疗反应的预测价值 .中华检验医学杂志，2014，37（2）:96-99

12.罗泽龙，冯超，赵剑波 .颈静脉肝穿刺活检术12例 .介入放射学杂志，2015，24（5）:446-448

13.欧启水 .核苷酸衍生物相关技术在分子诊断中的应用与展望 .实用检验医师杂志，2013，5（3）:133-136

14.汪月娥，张天嵩，范清琪，等.瞬时弹性成像技术对慢性丙型肝炎肝纤维化和肝硬化患者诊断价值的Meta 分析 .中华传染病杂志，2014，32（10）:616-621

15.王炜，陈晓，江凌，等 .HBV DNA定量与基因分型双重分子信标实时PCR方法的建立及初步应用 .中华检验医学杂志，2013，36（4）:333-338

16.许尚文，陈自谦，夏加林，等.扩散加权成像与超声弹性成像诊断乙型病毒性肝炎肝纤维化分级的对比研究 .中华放射学杂志，2016，50（7）:518-521

17.曾勇彬，刘灿，欧启水 .建设 HBV 耐药突变和基因分型实验诊断平台 .中华检验医学杂志，2014，37（2）:87-89

18.中华医学肝病学分会，中华医学会感染病学分会.丙型肝炎防治指南（2015年版）.中国肝脏病杂志（电子版），2015，7（3）:19-35

19.中华医学会肝病学分会，中华医学会感染病学分会.慢性乙型肝炎防治指南（2015更新版）.中华传染病杂志，2015，33（11）:641-662

20.中华医学会肝病学分会，中华医学会感染病学分会.慢性乙型肝炎防治指南（2015年版）.中国肝脏病杂志（电子版），2015，7（3）:1-18

21.中华医学会肝病学分会，中华医学会感染病学分会.慢性乙型肝炎防治指南（2015年版）.中华实验和临床感染病杂志（电子版），2015，9（5）:570-589

22.American Association for the Study of Liver Diseases，European Association for the Study of the Liver.Hepatic Encephalopathy in Chronic Liver Disease:2014 Practice Guideline by the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases.Journal of Hepatology，2014，61（3）:642-659

23.Zoller B，Spanaus K，Gerster R，et al.ICG-liver test versus new biomarkers as prognostic markers for prolonged length of stay in critically ill patients-a prospective study of accuracy for prediction of length of stay in the ICU.Ann Intensive Care，2014，4（19）:2-5

24.An C，Rakhmonova G，Choi JY，et al.Liver imaging reporting and data system（LI-RADS）version 2014:understanding and application of the diagnostic algorithm.Clin Mol Hepatol，2016，22（2）:296-307

25.Bohte AE，de Niet A，Jansen L，et al.Non-invasive evaluation of liver fibrosis:a comparison of ultrasound-based transient elastography and MR elastography in patients with viral hepatitis B and C.Eur Radiol，2014，24（3）:638-648

26.Bülow R，Mensel B，Meffert P，et al.Diffusion weighted magnetic resonance imaging for staging liver fibrosis is less reliable in the presence of fat and iron.Eur Radiol，2013，23（5）:1281-1287

27.Cece H，Ercan A，Yildiz S，et al.The use of DWI to assess spleen and liver quantitative ADC changes in the detection of liver fibrosis stages in chronic viral hepatitis.Eur J Radiol，2013，82（8）:e307-e312

28.Chin JL，Pavlides M，Moolla A，et al.Non-invasive Markers of Liver Fibrosis:Adjuncts or Alternatives to Liver Biopsy？Front Pharmacol，2016，7（1）:159

29.De Sio I，Iadevaia MD，Vitale LM，et al.Optimized contrast-enhanced ultrasonography for characterization of focal liver lesions in cirrhosis:A single-center retrospective study.United European Gastroenterol J，2014，2（4）:279-287

30.Di Costanzo GG，Tortora R，D'Adamo G，et al.Radiofrequency ablation versus laser ablation for the treatment of small hepatocellular carcinoma in cirrhosis:a randomized trial.J Gastroenterol Hepatol，2015，30（3）:559-565

31.Dyvome HA，Galea N，Nevers T，et al.Diffusion-weighted imaging of the liver with multiple b values:effect of diffusion gradient polarity and breathing acquisition on image quality and intravoxel incoherent motion parameters--a pilot study.Radiology，2013，266（3）:920-929

32.Facciorusso A，Serviddio G，Muscatiello N.Local ablative treatments for hepatocellular carcinoma:An updated review.World J Gastrointest Pharmacol Ther，2016，7（4）:477-489

33.Filingeri V，Francioso S，Sforza D，et al.A retrospective analysis of 1.011 percutaneous liver biopsies performed in patients with liver transplantation or liver disease:ultrasonography can reduce complications？Eur Rev Med Pharmacol Sci，2016，20（17）:3609-3617

34.Hope TA，Fowler KJ，Sirlin CB，et al.Hepatobiliary agents and their role in LI-RADS.Abdom Imaging，2015，40（3）:613-625

35.Hu KQ.Advances in clinical application of cryoablation therapy for hepatocellular carcinoma and metastatic liver tumor.J Clin Gastroenterol，2014，48（10）:830-836

36.Jacobs A.Radiofrequency Ablation for Liver Cancer.Radiol Technol，2015，86（6）:645-664

37.Kemp W，Levy M，Weltman M，et al.Australian Liver Association（ALA）expert consensus recommendations for the use of transient elastography in chronic viral hepatitis.J Gastroenterol Hepatol，2015，30（3）:453-462

38.Kim MN，Kim SU，Kim BK，et al.Long-term changes of liver stiffness values assessed using transient elastography in patients with chronic hepatitis B receiving entecavir.Liver Int，2014，34（8）:1216-1223

39.Leporq B，Dumortier J，Pilleul F，et al.3D-liver perfusion MRI with the MS-325 blood pool agent:a noninvasive protocol to asses liver fibrosis.J Magn Reson Imaging，2012，35（6）:1380-1387

40.Liu C，Chen T，Lin J，et al.Evaluation of the performance of four methods for detection of hepatitis B surface antigen and their application for testing 116，455 specimens.Journal of Virological Methods，2014，196:174-178

41.Liu C，Lin J，Chen H，et al.Detection of hepatitis B virus genotypic resistance mutations by coamplification at lower denaturation temperature-PCR coupled with sanger sequencing.Journal of Clinical Microbiology，2014，52（8）:2933-2939

42.Mhatre S，Madkaikar M，Ghosh K，et al.Rapid flow cytometry based cytotoxicity assay for evaluation of NK cell function.Indian J Exp Biol，2014，52（10）:983-988

43.Mitchell DG，Bruix J，Sherman M，et al.LI-RADS（liver imaging reporting and data system）:summary，discussion，and consensus of the LI-RADS management working group and future directions.Hepatology，2015，61（3）:1056-1065

44.Mizuguchi T，Kawamoto M，Meguro M，et al.Preoperative liver function assessments to estimate the prognosis and safety of liver resections.Surg Today，2014，44（1）:1-10

45.Mu D，Yan L，Tang H，et al.A sensitive and accurate quantification method for the detection of hepatitis B virus covalently closed circular DNA by the application of a droplet digital polymerase chain reaction amplification system.Biotechnol Lett，2015，37（10）:2063-2073

46.Pathak K，Gopinath M，Salgotra KR.Transjugular liver biopsy.Med J Armed Forces India，2013，69（4）:384-387

47.Piccinino F，Sagnelli E，Pasquale G，Complications following percutaneous liver biopsy.A multicentre retrospective study on 68，276 biopsies.J Hepatol，1986，2（2）:165-173

48.Platon ML，Stefanescu H，Feier D，et al.Performance of unidimensional transient elastography in staging chronic hepatitis C.Results from a cohort of 1，202 biopsied patients from one single center.J Gastrointestin Liver Dis，2013，22（2）:157-166

49.Sarin SK，Kumar M，Lau GK，et al.Asian-Pacific clinical practice guidelines on the management of hepatitis B:a 2015 update.Hepatology International，2016，10:1-98

50.Shin SK，Kim YS，Choi SJ，et al.Contrast-enhanced ultrasound for the differentiation of small atypical hepatocellular carcinomas from dysplastic nodules in cirrhosis.Dig Liver Dis，2015，47（9）:775-782

51.Singal AK，Kamath PS.Model for End-stage Liver Disease.J Clin Exp Hepatol，2013，3（1）:50-60

52.Takkenberg RB，Menting S，Beld MG.Validation of a sensitive and specific real-time PCR for detection and quantitation of hepatitis B virus covalently closed circular DNA in plasma of chronic hepatitis B patients.Methods Mol Biol，2012，903:113-128

53.Tedder RS，Tuke P，Wallis N，et al.Therapy-induced clearance of HCV core antigen from plasma predicts an end of treatment viral response.Journal of Viral Hepatitis，2013，20（1）:65-71.

54.Ura K，Furusyo N，Ogawa E，et al.Serum WFA（+）-M2BP is a non-invasive liver fibrosis marker that can predict the efficacy of direct-acting anti-viral-based triple therapy for chronic hepatitis C.Alimentary pharmacology &therapeutics，2016，43（1）:114-124

55.Vermehren J，Susser S，Berger A，et al.Clinical utility of the ARCHITECT HCV Ag assay for early treatment monitoring in patients with chronic hepatitis C genotype 1 infection.J Clin Virol，2012，55（1）:17-22

56.Wada Y，Tamai H，Uno A，et al.Prediction of efficacy to pegylated interferon-alpha-2b plus ribavirin in patients with genotype 2 hepatitis C virus using viral response within 2 weeks.Hepatology Research:the Official Journal of the Japan Society of Hepatology，2014，44（2）:179-186

57.Wakiya T，Kudo D，Toyoki Y，et al.Evaluation of the usefulness of the indocyanine green clearance test for chemotherapy-associated liver injury in patients with colorectal cancer liver metastasis.Ann Surg Oncol，2014，21（1）:167-172

58.Xu WS，Qiu XM，Ou QS，et al.Red blood cell distribution width levels correlate with liver fibrosis and inflammation:a noninvasive serum marker panel to predict the severity of fibrosis and inflammation in patients with hepatitis B.Medicine，2015，94（10）:e612

59.Yang N，Ekanem NR，Sakyi CA，et al.Hepatocellular carcinoma and microRNA:new perspectives on therapeutics and diagnostics.Advanced Drug Delivery Reviews，2015，81:62-74

60.Zeng Y，Li D，Wang W，et al.Establishment of real time allele specific locked nucleic acid quantitative PCR for detection of HBV YIDD（ATT）mutation and evaluation of its application.PLoS One，2014，9（2）:e90029

61.Zeng Y，Yang B，Wu Y，et al.Clinical significance of periodic detection of hepatitis B virus YVDD mutation by ultrasensitive real-time amplification refractory mutation system quantitative PCR during lamivudine treatment in patients with chronic hepatitis B.Journal of Medical Microbiology，2015，64（Pt 3）:237-242 gZPk7MG/G9xCZpzMXQ0DtWQykKM+jZHiSDjBpFbjrKQfs9KHH+j/7E6610geAAPW