参考文献

［1］ 李兆申，王贵齐．中国早期食管癌筛查及内镜诊治专家共识意见（2014年，北京）［J］．胃肠病学，2015（4）：220-240．

［2］ LY H, FC K, YP W, et al. Anxiety and depressive disorders among patients with esophageal cancer in Taiwan: a nationwide population-based study [J]. Support Care Cancer, 2015, 23 (3): 733-740.

［3］ SJ F, SM L, VAN WERVEN J R, et al. Psychological factors and preferences for communicating prognosis in esophageal cancer patients [J]. Psycho-oncology, 2009, 18 (11): 1199-1207.

［4］ 蔡琳，钟明洁，朱熊兆，等．抑郁性障碍患者的症状表现与认知情绪调节方式的关系［J］．中国临床心理学杂志，2012，20（2）：176-178．

［5］ 杨艳妮．《黄帝内经》防治情志病理论探析［J］．中医学报，2017，32（2）：246-249．

［6］ COOK M B, KAMANGAR F, WHITEMAN D C, et al. Cigarette smoking and adenocarcinomas of the esophagus and esophagogastric junction: a pooled analysis from the international BEACON consortium [J]. J Natl Cancer Inst, 2010, 102 (17): 1344-1353.

［7］ KAZ A M, WONG C J, VARADAN V, et al. Global DNA methylation patterns in Barrett’s esophagus,dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use [J]. Clin Epigenetics, 2016 (8): 111.

［8］ CHUNG C S, LEE Y C, WANG C P, et al. Secondary prevention of esophageal squamous cell carcinoma in areas where smoking, alcohol, and betel quid chewing are prevalent [J]. J Formos Med Assoc, 2010, 109 (6): 408-421.

［9］ LEE C H, WU D C, WU I C, et al. Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma diagnosis [J]. Int J Cancer, 2009, 125 (5): 1134-1142.

［10］ ISHIGURO S, SASAZUKI S, INOUE M, et al. Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study) [J]. Cancer Lett, 2009, 275 (2): 240-246.

［11］ SALASPURO V, SALASPURO M. Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva [J]. Int J Cancer, 2004, 111 (4): 480-483.

［12］ GOAN Y G, CHANG H C, HSU H K, et al. Risk of p53 gene mutation in esophageal squamous cell carcinoma and habit of betel quid chewing in Taiwanese [J]. Cancer Sci, 2005, 96 (11): 758-765.

［13］ WU I C, LU C Y, KUO F C, et al. Interaction between cigarette, alcohol and betel nut use on esophageal cancer risk in Taiwan [J]. Eur J Clin Invest, 2006, 36 (4): 236-241.

［14］ 韩书婧，魏文强，张澍田，等．食管癌高发地区人群危险因素的调查研究［J］．中国全科医学，2012，15（32）：3745-3748．

［15］ TERRY P, LAGERGREN J, HANSEN H, et al. Fruit and vegetable consumption in the prevention of oesophageal and cardia cancers [J]. Eur J Cancer Prev, 2001, 10 (4): 365-369.

［16］ KUBO A, CORLEY D A, JENSEN C D, et al. Dietary factors and the risks of oesophageal adenocarcinoma and Barrett’s esophagus [J]. Nutr Res Rev, 2010, 23 (2): 230-246.

［17］ ZHAO Y, GUO C, HU H, et al. Folate intake, serum folate levels and esophageal cancer risk: an overall and dose-response meta-analysis [J]. Oncotarget, 2017, 8 (6): 10458-10469.

［18］ 林璜，AU WW，欧利民．食管癌流行现状及潮汕食管癌病因学研究［J］．中国实用医药，2015，10（32）：277-279．

［19］ KESZEI A P, SCHOUTEN L J, GOLDBOHM R A, et al. Red and processed meat consumption and the risk of esophageal and gastric cancer subtypes in the netherlands cohort study [J]. Ann Oncol, 2012, 23 (9): 2319-2326.

［20］ ISLAMI F, BOFFETTA P, REN J S, et al. High-temperature beverages and foods and esophageal cancer risk—a systematic review [J]. Int J Cancer, 2009, 125 (3): 491-524.

［21］ 李鹏，王拥军，陈光勇，等．中国巴雷特食管及其早期腺癌筛查与诊治共识（2017万宁）［J］．中国实用内科杂志，2017（9）：798-809．

［22］ EL-SERAG H B, NAIK A D, DUAN Z, et al. Surveillance endoscopy is associated with improved outcomes of oesophageal adenocarcinoma detected in patients with Barrett’s oesophagus [J]. Gut, 2016, 65 (8): 1252-1260.

［23］ BENAGLIA T, SHARPIES L D, FITZGERALD R C, et al. Health benefits and cost effectiveness of endoscopic and nonendoscopic cytosponge screening for Barrett’s esophagus [J]. Gastroenterology, 2013, 144 (1): 62-73.

［24］ PROBST A, AUST D, MARKL B, et al. Early esophageal cancer in Europe: endoscopic treatment by endoscopic submucosal dissection [J]. Endoscopy, 2015, 47 (2): 113-121.

［25］ 李鹏，陈光勇，王拥军，等．中国早期食管鳞状细胞癌及癌前病变筛查与诊治共识（2015年·北京）[J］．中华消化内镜杂志，2016，33（1）：3-18．

［26］ ISHIHARA R, IISHI H, UEDO N, et al. Comparison of EMR and endoscopic submucosal dissection for en bloc resection of early esophageal cancers in Japan [J]. Gastrointest Endosc, 2008, 68 (6): 1066-1072.

［27］ PANDEYA N, OLSEN C M, WHITEMAN D C. Sex differences in the proportion of esophageal squamous cell carcinoma cases attributable to tobacco smoking and alcohol consumption [J]. Cancer Epidemiol, 2013, 37 (5): 579-584.

［28］ SHAHEEN N J, WEINBERG D S, DENBERG T D, et al. Upper endoscopy for gastroesophageal reflux disease: best practice advice from the clinical guidelines committee of the American College of Physicians [J]. Ann Intern Med, 2012, 157 (11): 808-816.

［29］ LIAO L M, VAUGHAN T L, CORLEY D A, et al. Nonsteroidal anti-inflammatory drug use reduces risk of adenocarcinomas of the esophagus and esophagogastric junction in a pooled analysis [J]. Gastroenterology, 2012, 142 (3): 442-452.

［30］ ROTHWELL P M, FOWKES F G, BELCH J F, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials [J]. Lancet, 2011, 377 (9759): 31-41.

［31］ United Nations, Department of Economic and Social Affairs, Population Division. World Contraceptive Use 2015. (New York: United Nations). Available at http://www.un.org/en/development/desa/population/publications/dataset/contraception/wcu2015.shtml.

［32］ LAGERGREN K, LAGERGREN J, BRUSSELAERS N. Hormone replacement therapy and oral contraceptives and risk of esophageal adenocarcinoma: a systematic review and meta-analysis [J]. Int J Cancer, 2014, 135 (9): 2183-2190.

［33］ BRUSSELAERS N, MARET-OUDA J, KONINGS P, et al. Menopausal hormone therapy and the risk of esophageal and gastric cancer [J]. Int J Cancer, 2017, 140 (7): 1693-1699.

［34］ CRONIN-FENTON D P, MURRAY L J, WHITEMAN D C, et al. Reproductive and sex hormonal factors and esophageal and gastric junction adenocarcinoma: a pooled analysis [J]. Eur J Cancer, 2010, 46 (11): 2067-2076.

［35］ SINGH S, GARG S K, SINGH P P, et al. Acid-suppressive medications and risk of esophageal adenocarcinoma in patients with Barrett’s esophagus: a systematic review and meta-analysis [J]. Gut, 2014, 63 (8): 1229-1237.

［36］ HU Q, SUN T T, HONG J, et al. Proton pump inhibitors do not reduce the risk of esophageal adenocarcinoma in patients with Barrett’s esophagus: a systematic review and meta-analysis [J]. PLoS One, 2017, 12 (1): e0169691.

［37］ MARET-OUDA J, KONINGS P, LAGERGREN J, et al. Antireflux surgery and risk of esophageal adenocarcinoma: a systematic review and meta-analysis [J]. Ann Surg, 2016, 263 (2): 251-257.

（吴丽权　谢文瑞　叶志宁） uC8o0kdW+pVA0V2SN3/VCRWDkVAjV4T/RRVXWwXV7DaYAivAeQ8KMDT0+PFCvk6N