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四、随访

外阴癌局部复发如能及时发现、及时治疗,预后较好。因此,长期的随访是必要的,建议随访间隔时间:①第1年,每3个月1次;②第2~3年,每3~6个月1次;③3年后,每年1次。

(刘继红 黄 鹤 李玉洁 李孟达 王建六)

参考文献

1.Pecorelli S.Revised FIGO staging for carcinoma of the vulva,cervix,and endometrium.Int J Gynaecol Obstet,2009,105(2):103-104.

2.Tabbaa ZM,Gonzalez J,Sznurkowski JJ,et al.Impact of the new FIGO 2009 staging classification for vulvar cancer on prognosis and stage distribution.Gynecol Oncol,2012,127(1):147-152.

3.Levenback CF,Ali S,Coleman RL,et al.Lymphatic mapping and sentinel lymph node biopsy in women with squamous cell carcinoma of the vulva:a gynecologic oncology group study.J Clin Oncol,2012,30(31):3786-3791.

4.Berek JS,Hacker NF.Berek&Hacker's gynecologic oncology.Philadelphia:Wolters Kluwer/Lippincott Williams&Wilkins Health.6th ed.2014.

5.Stephan Polterauer,Richard Schwameis,Christoph Grimm,et al.Lymph node ratio in inguinal lymphadenectomy for squamous cell vulvar cancer:Results from the AGO-CaRE-1 study.Gynecol Oncol,2019,153:286-291.

6.Chapman PB,Robert C,Larkin J,et al.Vemurafenib in patients with BRAF V600 mutation-positive metastatic melanoma:final overall survival results of the randomized BRIM-3 study.Annals of Oncology,2017,28:2581-2587.

7.Caroline Robert,Antoni Ribas,Omid Hamid,et al.Durable complete response after discontinuation of pembrolizumab in patients with metastatic melanoma.J Clin Oncol,2018,36(17):1668-1674. qE9+uAPeF5zrF0ecGH3khpR07/GKX0PbLhnRfVJiPaZVyEe6If81g3bQTLzYI4zd

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