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“Acupuncture” and “Moxibustion” are two main therapies in acupuncture and moxibustion medicine. The scientific researches have concluded that moxibustion therapy offers unique advantages over certain diseases, especially in enhancing the function of the immune system. In view of the rapid expansion of the use of acupuncture and moxibustion worldwide, setting up the standard of the manipulation for moxibustion therapy is extremely important in order to clarify its proper application, enhance its effectiveness, and reduce or avoid its side effects.